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Sr Clinical Pharmacologist

Company: Horizon Therapeutics
Location: Vernon Hills
Posted on: March 19, 2023

Job Description:

Job Description:

At Horizon Therapeutics, we define success by the number of lives touched, lives changed, and lives saved. Our global biotechnology company is made up of agile, out-of-the-box thinkers with a focus on delivering breakthrough medicines to those living with rare, autoimmune, and severe inflammatory diseases. This is the heart of our global mission. Start a career that enables you to live up to your potential and help others live up to theirs. Join us. The exceptional support we provide patients and communities equally extends to our employees. We offer industry-leading and award-winning benefits, compensation and rewards programs that positively impact all areas of our employees' personal and professional lives. Position Summary: Support clinical pharmacology and DMPK function from pre-IND to post approval for small and/or large molecules.Responsibilities:Support clinical pharmacology and DMPK function from pre-IND to post approval for both small and large molecules in all therapeutic areasUnder the guidance of clinical pharmacology lead,Collaborate with toxicologist and preclinical pharmacology scientists to design, analyze, interpret, and report preclinical PK and translational PK/PD studies to support candidate selection and IND filing, including human PK prediction to support starting dose and dose escalation schemes for first-in-man studiesDesign clinical pharmacology studies and perform PK data analysis for data interpretationPerform and/or oversee population PK, PK/PD, and exposure-response analysis to support dose selectionsPresent clinical pharmacology and DMPK results to internal and external stakeholdersContribute to author nonclinical, clinical and regulatory documents related to DMPK and clinical pharmacology components, including protocols, study reports, INDs, IBs, briefing documents for regulatory meetings, and NDA/BLA; author scientific publicationsWork closely with collaborators and CROs in study protocol/report review for both preclinical and clinical studiesQualifications and Skills Required:-3 years of industry or equivalent experience and an MD, PhD or PharmD degree in pharmacokinetics, pharmacometrics, clinical pharmacology or other related disciplinesFamiliar with Phoenix WinNonlinExperience in mathematical modeling and programming (e.g. R, NONMEM) is preferredDemonstrated ability to work in a highly collaborative, multi-disciplinary team settingSelf-directed and motivated researcher, with willingness to learn new tools and approachesExcellent written and verbal communication skills#LI-REMOTE Our Values Transparency: We value collaboration. Trusting teach other and tackling tough challenges can make a powerful differenceAccountability: We do what's right for our patient communities through quality decisions and owning our successes and failuresGrowth: We fiercely innovate and evolve to better ourselves, our communities and our patientsThese three values come to life through our five Leadership Expectations that apply to all Horizon employeesEnterprise Mindset: Look beyond one's team, brand or function to see the broader company and external perspectiveExhibit Intellectual Curiosity: Seek to understand what you do not know; ask the right questions of the right people and sourcesEnsure Accountability and Courage: Step up to address difficult issues and hold self and others accountable to commitmentsEmbrace Diverse Perspectives: Welcome others with a respectful attitude; integrate diverse perspectives into ways of workingDevelop Talent: Provide feedback, coaching and mentorship to help others be more effective in their roleOur ValuesTransparency: We value collaboration. Trusting teach other and tackling tough challenges can make a powerful difference.Accountability: We do what's right for our patient communities through quality decisions and owning our successes and failures.Growth: We fiercely innovate and evolve to better ourselves, our communities and our patients.These three values come to life through our five Leadership Expectations that apply to all Horizon employeesEnterprise Mindset: Look beyond one's team, brand or function to see the broader company and external perspectiveExhibit Intellectual Curiosity: Seek to understand what you do not know; ask the right questions of the right people and sourcesEnsure Accountability and Courage: Step up to address difficult issues and hold self and others accountable to commitmentsEmbrace Diverse Perspectives: Welcome others with a respectful attitude; integrate diverse perspectives into ways of workingDevelop Talent: Provide feedback, coaching and mentorship to help others be more effective in their roleCompensation and Benefits Summary:The salary range for this role is $144,000.00-$176,000.00 annually. The base salary offered may vary based on the final candidate's qualifications. The level of this role may also change based on the final candidate's qualifications.In addition to the salary, this position is eligible for the benefits listed here and for the following plans:Salary Plan, Annual Merit Plan, Annual Equity Grant, New Hire Equity Grant, Corporate BonusAt Horizon, we know that disease does not discriminate. We embrace the bold ideas of one another, foster a sense of belonging, and value inclusion. We attract and develop diverse talent because we believe that when people from different backgrounds and life experiences come together, we make lives better. Horizon intends that all qualified applications are given equal opportunity, and that selection decisions be based on job-related factors. We do not discriminate based on race, color, religion, gender, sexual orientation, national origin, age, disability, veteran status, or any other characteristics protected by law.

Keywords: Horizon Therapeutics, Arlington Heights , Sr Clinical Pharmacologist, Healthcare , Vernon Hills, Illinois

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